24.05.18 (THURSDAY), 12.30-13.00: Intergenerational influences on behavior and cognition (abstract here)


Dan Ehninger is a Senior Research Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn. He studied medicine at Charité University Medicine/Berlin, Harvard Medical School/Boston and University College London. From 2001 to 2004, he carried out his graduate work in the laboratory of Gerd Kempermann at the Max Delbrück Center for Molecular Medicine in Berlin, where he worked on the behavioral regulation of adult hippocampal neurogenesis and adult cell formation in the neocortex. His postdoctoral work (2004 to 2009) with Alcino Silva at University of California – Los Angeles focused on molecular and cellular mechanisms of cognitive impairments in mouse models of neuropsychiatric disorders. In 2010, Dan Ehninger joined the faculty of the German Center for Neurodegenerative Diseases (DZNE). He gained Habilitation in Neuroscience at the Medical Faculty of the University of Bonn in 2016 and was promoted to a tenured Senior Research Group Leader position at the DZNE in 2017.

Dan Ehninger has a long-standing interest in mechanisms of neuropsychiatric disorders, which he explores in suitable mouse models (e.g., Ehninger et al., Nat Med 2008; Neuron 2008; Ehninger et al., Mol Psychiatry 2012; Zhou et al., Neuron 2013; Lee et al., Nat Neurosci 2014). Current work in his laboratory is also focused on clarifying the role of key lifespan-regulatory pathways in influencing aging and the pathogenesis of age-related disorders (e.g., Neff et al., J Clin Invest 2013; Xie et al., Nat Commun 2017; Bellantuono et al., Nature 2018). He is also interested in addressing if and how age-related, as well as environmentally induced epigenetic changes interact with health and disease outcomes, both in directly exposed individuals, as well as possibly inter- and/or transgenerationally (e.g., Ryan et al., Mol Psychiatry 2017; Henzel et al., Sci Rep 2017; Xie et al., PNAS 2018).