Title of my talk: Angiomotins. A small family (of scaffold proteins) but so influential that you can lose your mind.
Bio: Tomasz J. Prószyński is a head of Laboratory of Synaptogenesis at the Nencki Institute of Experimental Biology of Polish Academy of Sciences in Warsaw, Poland. His laboratory studies mechanisms underlying organization of neuromuscular junctions in the peripheral nervous system and neuronal organization in the brain. Tomasz Prószyński obtained his Ph.D. title at the Max-Planck Institute for Cell Biology and Genetics in Dresden, Germany, where he worked on yeast cell biology. After graduation, he obtained his post-doctoral training at Harvard University where he started to work on skeletal muscles. His particular interest was focused on the molecular and cellular mechanisms regulating postnatal remodeling of the neuromuscular junctions. His work revealed that podosome-like organelles are implicated in developmental remodeling of the postsynaptic machinery. His most recent projects include studies on the function of Angiomotin family of proteins in the organization of neurons and brain functions. He demonstrated that Amot interaction with the transcription co-activator Yap1 controls development of the dendritic tree complexity through regulation of S6 kinase activity and phosphorylation of ribosomal protein S6.